产品说明
一般描述
The PDGFRB (platelet derived growth factor receptor β) gene is mapped to human chromosome 5q32. It encodes for a receptor tyrosine kinase.
Anti-PDGFRB antibody detects endogenous levels of total PDGFRB protein.
免疫原
The antiserum was produced against synthesized peptide derived from human PDGFRB.
Immunogen Range: 981-1030
应用
Anti-PDGFRB, C-Terminal antibody produced in rabbit has been used in immunohistochemistry analysis.
生化/生理作用
PDGFRB (platelet derived growth factor receptor β) acts as a regulator of mesenchymal cells in tumor cells. Upregulation of the gene is observed in gastric cancer, breast and prostate cancers. Mutations in the gene is associated with infantile myofibromatosis.
特点和优势
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外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
分子量 | antigen 123 kDa |
species reactivity | mouse, human, rat |
浓度 | ~1 mg/mL |
technique(s) | ELISA: 1:20000 immunofluorescence: 1:100-1:500 immunohistochemistry: 1:50-1:100 |
NCBI登记号 | P09619 |
UniProt登记号 | P09619 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... PDGFRB(5159) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | nwg |
闪点(F) | Not applicable |
闪点(C) | Not applicable |