产品介绍：
产品说明
应用
Ro 15-4513 has been used as a benzodiazepine (Bz) inverse agonist in rats and to test its binding with diazepam-sensitive (DS) receptors in in vitro radioligand binding studies.
包装
25, 100 mg in poly bottle
生化/生理作用
Ro 15-4513 is benzodiazepine receptor partial inverse agonist. It elicits anxiogenic property and is an ethanol antagonist. It elicits a high affinity towards diazepam sensitive and insensitive sites in the cerebellar region. Ro 15-4513 possesses an imidazo ring and is an imidazobenzodiazepine.
特点和优势
This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
基本信息
| 经验(实验)分子式 | C15H14N6O3 |
| 分子量 | 326.31 |
| MDL编号 | MFCD00078598 |
| PubChem化学物质编号 | 24899343 |
产品性质
| 质量水平 | 100 |
| 形式 | solid |
| 颜色 | tan |
| 溶解性 | 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.8 mg/mL H2O: insoluble methanol: soluble |
| 创始人 | Roche |
| SMILES string | CCOC(=O)c1ncn-2c1CN(C)C(=O)c3cc(ccc-23)N=[N+]=[N-] |
| InChI | 1S/C15H14N6O3/c1-3-24-15(23)13-12-7-20(2)14(22)10-6-9(18-19-16)4-5-11(10)21(12)8-17-13/h4-6,8H,3,7H2,1-2H3 |
| InChI key | CFSOJZTUTOQNIA-UHFFFAOYSA-N |
| Gene Information | human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA5(2558), GABRA6(2559) rat ... Gabrg1(140674) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
