产品说明
一般描述
VPC 12249 is an N-acyl (oleoyl) serine phosphate-based compound.
应用
VPC 12249 has been used as lysophosphatidic acid (LPA)1/3 receptor antagonist in various experimental studies.
生化/生理作用
Lysophosphatidic acids (LPAs) are bioactive lipid mediators. It interacts with at least six specific LPA receptors (LPA1-6) to mediate extracellular signaling pathway. LPA and its receptors (LPA1-3) are implicated in the pathogenesis of radiation pneumonitis (RP). VPC 12249 (S) inhibits the binding ofLPA to LPA1 and LPA3 receptor.
包装
5 mL Amber Glass Screw Cap Vial (857341P-1mg)
基本信息
经验(实验)分子式 | C34H55N2O6P |
分子量 | 618.78 |
NACRES | NA.25 |
产品性质
测定 | >99% (TLC) |
形式 | powder |
包装 | pkg of 1 × 1 mg (857341P-1mg) |
manufacturer/tradename | Avanti Polar Lipids 857341P |
运输 | dry ice |
储存温度 | −20℃ |
SMILES string | O=C(CCCCCCC/C=C\CCCCCCCC)N[C@H](COP(O)([O-])=O)CC1=CC=C(OCC2=CC=CC=C2)C=C1.[NH4+] |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |