产品介绍：
产品说明
一般描述
Follicular fluid meiosis-activating sterol (FF-MAS) is an intermediate in the cholesterol biosynthetic pathway present in all cells, and may represent the physiological signal that instructs the oocyte to reinitiate meiosis.
应用
FF-MAS has been used:
- as a standard in gas chromatography/ mass spectroscopy (GC/MS) for profiling sterols of oligodendrocyte progenitor cells (OPCs)
- as Dulbecco′s modified eagle medium (DMEM) medium supplement to test its effect on cancer cell viability
- to evaluate its effect on LXRβ-overexpressing squamous carcinoma SCC61 cells
生化/生理作用
14-demethyl-14-dehydrolanosterol (FF-MAS) was first identified in follicular fluid of women and plays a key role in oocyte nuclear maturation. The levels of FF-MAS may be regulated by cytochrome P450 family 27 subfamily A member 1. Supplementation of FF-MAS to oocytes promotes meiotic maturation favoring preimplantation. However, FF-MAS has low solubility and is metabolized to cholesterol rapidly.
包装
5 mL Amber Glass Screw Cap Vial (700077P-1mg)
基本信息
| 经验(实验)分子式 | C29H46O |
| 分子量 | 410.67 |
| NACRES | NA.25 |
产品性质
| 测定 | >99% (TLC) |
| 形式 | powder |
| 包装 | pkg of 1 × 1 mg (700077P-1mg) |
| manufacturer/tradename | Avanti Polar Lipids 700077P |
| 运输 | dry ice |
| 储存温度 | −70℃ |
| InChI | 1S/C29H46O/c1-19(2)9-8-10-20(3)22-12-13-23-21-11-14-25-27(4,5)26(30)16-18-29(25,7)24(21)15-17-28(22,23)6/h9,13,20,22,25-26,30H,8,10-12,14-18H2,1-7H3/t20-,22-,25+,26+,28-,29-/m1/s1 |
| InChI key | LFQXEZVYNCBVDO-PBJLWWPKSA-N |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
