产品说明
一般描述
C12-NBD Phytosphingosine is a fluorescent derivative of the naturally occurring lipid compound, phytosphingosine which is localised in skin, kidney and intestines.
Phytosphingosine is a ceramide molecule localized to the stratum corneum.
应用
C12-NBD phytosphingosine has been used as a substrate to assay ceramidase activity.
C12-NBD Phytosphingosine has been used as a substrate in ceramidase activity assay to study enzyme activity.
生化/生理作用
Phytosphingosine (PHS) is a sphingoid lipid molecule which is known to exhibit antimicrobial and anti-inflammatory action. PHS can has the ability to increase the production of keratinocyte differentiation marker proteins, such as transglutaminase 1 and involucrin, that are responsible for the development of cornifed envelope. PHS metabolism results in the formation of glycerophospholipids, sphingolipids and even-numbered fatty acids which mainly include palmitic acid.
In vitro studies using human epidermis model shows that melanin production is prevented by phytosphingosine. Hence, it is widely used in cosmetics.
包装
5 mL Amber Glass Screw Cap Vial (810215P-50ug)
基本信息
| 经验(实验)分子式 | C36H63N5O7 |
| 分子量 | 677.91 |
| NACRES | NA.25 |
产品性质
| 测定 | >99% (TLC) |
| 形式 | powder |
| 包装 | pkg of 1 × 50 μg (810215P-50ug) |
| manufacturer/tradename | Avanti Polar Lipids 810215P |
| 运输 | dry ice |
| 储存温度 | −20℃ |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
