产品说明
一般描述
Peroxisome proliferator-activated receptors (PPARs) are a group of closely related nuclear receptors. Three PPAR isotypes have been identified: α,β (also called NUC1) and γ. PPARa mRNA is expressed most in brown adipose tissue, heart, liver and kidney in rats. The gene encoding PPARα is localized on human chromosome 22q12-q13.1 and rat chromosome 7q34.
免疫原
purified recombinant PPARα protein.
生化/生理作用
Peroxisome proliferator-activated receptors (PPARs) may be involved in chronic diseases such as diabetes, obesity, atherosclerosis and cancer. PPARα has a protective function in fatty acids overload associated tubular injury. The enzyme also has a role in fatty acid oxidation and metabolism.
外形
Solution in phosphate buffered saline containing 1 mg/ml bovine serum albumin and 0.05% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD01092469 |
| NACRES | NA.41 |
产品性质
| 质量水平 | 200 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | 3B6/PPAR, monoclonal |
| 形式 | buffered aqueous solution |
| species reactivity | rat, mouse, human |
| 浓度 | ~1 mg/mL |
| technique(s) | western blot: 2-5 μg/mL using human, mouse and rat |
| 同位素/亚型 | IgG2b |
| UniProt登记号 | Q07869 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... PPARA(5465) mouse ... Ppara(19013) rat ... Ppara(25747) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
