产品说明
一般描述
18:1 PI(3,4)P2 (1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′-bisphosphate)) is an ammonium salt of modified lipid.
Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.
应用
18:1 PI(3,4)P2 (1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′-bisphosphate) (ammonium salt)) has been used:
- in liposomes/supported lipid bilayer preparation
- in liposome co-sedimentation
- in the preparation of anionic phospholipid liposomes
生化/生理作用
PI(3,4)P2 can act as a lipid second messenger. In mast cells, PI(3,4)P2 plays a key role in protein kinase B (PKB) phosphorylation on Ser473 sites.
包装
2 mL Amber Serum Vial with Stopper and Crimp Cap (850153P-500ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850153P-100ug)
基本信息
经验(实验)分子式 | C45H94N3O19P3 |
分子量 | 1074.16 |
NACRES | NA.25 |
产品性质
测定 | >99% (TLC) |
形式 | powder |
包装 | pkg of 1 × 100 μg (with stopper and crimp cap (850153P-100ug)) pkg of 1 × 500 μg (with stopper and crimp cap (850153P-500ug)) |
manufacturer/tradename | Avanti Polar Lipids 850153P |
运输 | dry ice |
储存温度 | −20℃ |
SMILES string | [H][C@@](COP(O[C@H]1[C@H](O)[C@@H](O)[C@H](OP(O)([O-])=O)[C@@H](OP(O)([O-])=O)[C@H]1O)([O-])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+].[NH4+].[NH4+] |
安全信息
储存分类代码 | 13 - Non Combustible Solids |