产品说明
一般描述
Lysophosphatidylinositol (LPI), a degradation product of phosphatidylinositol (PI) is a lysophospholipid subspecies, which carries inositol in its head group.
应用
17:1 Lyso PI (1-(10Z-heptadecenoyl)-2-hydroxy-sn-glycero-3-phospho-(1′-myo-inositol)) has been used as an internal standard in LC-MS of mice brain lipidomic analysis. It may be used as internal standard in for the analysis of lysophosphatidylinositols (LPIs) in mice using high-performance liquid chromatography/electrospray ionization tandem mass spectrometry (HPLC/ESI-MS) and in the quantification of lysoPI (LPI) in livers of chronic high-fat diet (HFD)-fed WT and KO mice using liquid chromatography with tandem mass spectrometry (LC-MS-MS) system.
生化/生理作用
Increased circulating levels of L-alpha-lysophosphatidylinositol (LPI) are associated with cancer and LPI is a potent ligand for the G-protein-coupled receptor GPR55.
Lysophosphatidylinositol (LPI) serve as a bioactive lysophospholipid mediator. It favors mitogenic activity in quiescent fibroblasts. LPI has the ability to block hippocampal neuronal death in conditions of forebrain ischemia.
包装
2 mL Amber Serum Vial with Stopper and Crimp Cap (850103P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850103P-500ug)
基本信息
| 经验(实验)分子式 | C26H52NO12P |
| 分子量 | 601.66 |
| NACRES | NA.25 |
产品性质
| 测定 | >99% (LPI; may contain up to 10% of the 2-LPI isomer, TLC) |
| 形式 | powder |
| 包装 | pkg of 1 × 100 μg (with stopper and crimp cap (850103P-100ug)) pkg of 1 × 500 μg (with stopper and crimp cap (850103P-500ug)) |
| manufacturer/tradename | Avanti Polar Lipids 850103P |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| SMILES string | [H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(O)COC(CCCCCCCC/C=C\CCCCCC)=O.[NH4+] |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | No data available |
| 闪点(C) | No data available |
