产品说明
一般描述
Sphinganine (d18:0) is a substrate for the enzyme ceramide desaturase. It is synthesized indirectly due to the interconversion of supplemented glycine to serine. Sphinganine (d18:0) is catabolized to ceramide.
应用
Sphinganine (d18:0) has been used:
- as a standard in liquid chromatography tandem mass spectrophotometry for the quantification of epidermal ceramides
- as a medium supplement to test its effect on growth of yeast cells
- in the preparation of bovine serum albumin lipid complex to investigate its effect on non-lysosomal - glucosylceramidase β2 (GBA2) inhibition
生化/生理作用
Sphinganine (d18:0) levels are not altered in hereditary sensory neuropathy type 1 cells. Accumulation of d18:0 is observed in tumor hypoxia. It is useful as a biomarker for studying microbial diversity.
包装
5 mL Amber Glass Screw Cap Vial (860498P-25mg)
5 mL Amber Glass Screw Cap Vial (860498P-100mg)
5 mL Amber Glass Screw Cap Vial (860498P-10mg)
基本信息
经验(实验)分子式 | C18H39NO2 |
分子量 | 301.51 |
NACRES | NA.25 |
产品性质
形式 | powder |
包装 | pkg of 1 × 10 mg (860498P-10mg) pkg of 1 × 100 mg (860498P-100mg) pkg of 1 × 25 mg (860498P-25mg) |
manufacturer/tradename | Avanti Polar Lipids 860498P |
运输 | dry ice |
储存温度 | −20℃ |
SMILES string | OC[C@@](N)([H])[C@]([H])(O)CCCCCCCCCCCCCCC |
InChI | 1S/C18H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h17-18,20-21H,2-16,19H2,1H3/t17-,18+/m0/s1 |
InChI key | OTKJDMGTUTTYMP-ZWKOTPCHSA-N |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |