产品介绍：
产品说明
应用
Osteopontin from mouse has been used:
- to study its role in a mouse model of preterm brain injury
- as a positive control to analyze the relationship between the vascular calcification process and osteopontin (OPN) overexpression in the neointima of atherosclerotic plaques
- to study its interaction on the crystal growth process of hydroxyapatite in agarose hydrogels
生化/生理作用
Osteopontin (OPN) is a secreted, highly acidic, calcium binding, phosphorylated glycoprotein that is chemotactic for macrophages, smooth muscle cells, endothelial cells and glial cells. In activated macrophages, OPN inhibits nitric oxide production and cytotoxicity. Human, mouse, rat, pig and bovine OPN share 40% amino acid sequence identity.
外形
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 2.5 mg bovine serum albumin.
分析说明
The biological activity is measured by its ability to mediate 293 cell adhesion.
基本信息
| MDL编号 | MFCD03100698 |
| NACRES | NA.32 |
产品性质
| 质量水平 | 100 |
| 生物来源 | mouse |
| 重组 | expressed in NSO cells |
| 无菌性 | sterile |
| 测定 | >95% (SDS-PAGE) |
| 形式 | lyophilized powder |
| 分子量 | 30 kDa by SDS-PAGE (reducing) 65 kDa by SDS-PAGE (reducing) (doublet) |
| 包装 | pkg of 50 μg |
| technique(s) | cell culture | mammalian: suitable |
| 杂质 | endotoxin, tested |
| UniProt登记号 | P10923 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | mouse ... Spp1(20750) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
