产品介绍：
产品说明
一般描述
Alantolactone is a compound produced by Inula helenium. Alantolactone has antibacterial, antifungal, anti-inflammatory and anticancer properties. It suppresses signal transducer and activator of transcription 3 (STAT3) activation in liver and breast cancer cells. Alantolactone induces apoptosis in A549 lung cancer cells.
应用
Alantolactone has been used:
- in cell viability assay
- to examine the percentage of multicentrosomal mitosis in low and high passage human embryonic stem cells (hESC)
- in assessment of degranulation
包装
5, 25 mg in glass bottle
生化/生理作用
Alantolactone is a sesquiterpene lactone disrupts the Cripto-1/ActRII complexes, resulting in an induction of activin/SMAD3 signaling. Alantolactone inhibits proliferation in cancer cells with no affect on normal cells.
基本信息
| 经验(实验)分子式 | C15H20O2 |
| 分子量 | 232.32 |
| EC 号 | 208-899-3 |
| MDL编号 | MFCD00274568 |
| PubChem化学物质编号 | 329825410 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 储存条件 | desiccated protect from light |
| 颜色 | white to beige |
| 溶解性 | DMSO: 15 mg/mL (clear solution) |
| 储存温度 | −20℃ |
| SMILES string | C[C@H]1CCC[C@]2(C)C[C@H]3OC(=O)C(=C)[C@H]3C=C12 |
| InChI | 1S/C15H20O2/c1-9-5-4-6-15(3)8-13-11(7-12(9)15)10(2)14(16)17-13/h7,9,11,13H,2,4-6,8H2,1,3H3/t9-,11+,13+,15+/m0/s1 |
| InChI key | PXOYOCNNSUAQNS-AGNJHWRGSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H317 |
| 预防措施声明 | P261 - P272 - P280 - P333 + P313 - P362 + P364 - P501 |
| 危险分类 | Skin Sens. 1 |
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
