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Alantolactone

品牌
Sigma-Aldrich
CAS
546-43-0
货号
SML0415
规格纯度
≥98% (HPLC)
参考价格
1032.8 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Alantolactone is a compound produced by Inula helenium. Alantolactone has antibacterial, antifungal, anti-inflammatory and anticancer properties. It suppresses signal transducer and activator of transcription 3 (STAT3) activation in liver and breast cancer cells. Alantolactone induces apoptosis in A549 lung cancer cells.

应用

Alantolactone has been used:

  • in cell viability assay
  • to examine the percentage of multicentrosomal mitosis in low and high passage human embryonic stem cells (hESC)
  • in assessment of degranulation

包装

5, 25 mg in glass bottle

生化/生理作用

Alantolactone is a sesquiterpene lactone disrupts the Cripto-1/ActRII complexes, resulting in an induction of activin/SMAD3 signaling. Alantolactone inhibits proliferation in cancer cells with no affect on normal cells.

基本信息

经验(实验)分子式C15H20O2
分子量232.32
EC 号208-899-3
MDL编号MFCD00274568
PubChem化学物质编号329825410
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
储存条件desiccated
protect from light
颜色 white to beige
溶解性DMSO: 15 mg/mL (clear solution)
储存温度−20℃
SMILES stringC[C@H]1CCC[C@]2(C)C[C@H]3OC(=O)C(=C)[C@H]3C=C12
InChI1S/C15H20O2/c1-9-5-4-6-15(3)8-13-11(7-12(9)15)10(2)14(16)17-13/h7,9,11,13H,2,4-6,8H2,1,3H3/t9-,11+,13+,15+/m0/s1
InChI keyPXOYOCNNSUAQNS-AGNJHWRGSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H317
预防措施声明P261 - P272 - P280 - P333 + P313 - P362 + P364 - P501
危险分类Skin Sens. 1
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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