产品说明
一般描述
Noggin (NOG) is a protein first identified in Xenopus-italics that plays a vital role in the dorsal fate specification during embryogenesis. A similar protein was also found in mammals and is vital during the various processes of morphogenesis. Noggin is mainly expressed in specific regions of brain such as cerebellum, olfactory bulb, and the piriform cortex. It interacts with various transcription factors such as Wnt, Hox, Sox, Pax and Pou gene products. Noggin has been identified as an inhibitor of the TGF-β signalling pathway and is involved in neural induction and maturation of neurons, in development of the central nervous system. Noggin is also essential for skeletogenesis and bone joint formation and in development of heart
Anti-Noggin recognizes human noggin.
免疫原
synthetic peptide corresponding to an internal sequence of human Noggin. This sequence is identical in rat and mouse.
应用
Anti-Noggin antibody is suitable for immunoblotting at a recommended working dilution of 1:1000 to 1:2000.
外形
solution in phosphate buffered saline, containing 0.02% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 200 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| species reactivity | human |
| 浓度 | ~1 mg/mL |
| technique(s) | western blot: 1:1,000-1:2,000 |
| UniProt登记号 | Q13253 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... NOG(9241) mouse ... Nog(18121) rat ... Nog(25495) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
