产品说明
一般描述
Na+/Ca2+ exchanger is also known as solute carrier family 8 member A1 (SLC8A1) and is present in the plasma membrane. It is predicted to have nine transmembrane segments and the gene encoding SLC8A1 has three promoters.
特异性
The antibody reacts specifically with Na+/Ca2+ exchanger in kidney and cardiac tissues. By immunohistology, staining of the plasma membrane and intense staining of the cardiac T-tubular membrane is observed. The antibody is not recommended for immunoblotting of rat tissues.
免疫原
dog cardiac Na+/Ca2+ exchanger. The epitope is in the region of amino acids 371-525, which is on the intracellular side of the plasma membrane.
生化/生理作用
Na+/Ca2+ exchanger (SLC8A1, solute carrier family 8 member A1) is involved in Ca2+ homeostasis. Depending on physiological conditions prevailing in the cell, it can either pump out Na+ or Ca2+.
外形
Solution in phosphate buffered saline, 1 mg/ml BSA containing 0.05% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD01865491 |
| NACRES | NA.41 |
产品性质
| 质量水平 | 200 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| antibody product type | primary antibodies |
| 克隆 | C2C12, monoclonal |
| 形式 | liquid |
| 分子量 | antigen 120 kDa (mature exchanger) antigen 160 kDa (non-reduced) antigen 70 kDa (proteolytic fragment) |
| species reactivity | canine, rat, guinea pig, human, rabbit |
| technique(s) | immunohistochemistry (frozen sections): 1:200 immunoprecipitation (IP): suitable western blot: 1:1,000 |
| 同位素/亚型 | IgM |
| UniProt登记号 | P32418 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... SLC8A1(6546) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
