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Src Protein, 10 μg

品牌
Sigma-Aldrich
货号
23-042-M
规格纯度
Full length, recombinant human Src. N-terminal c-Myc, 6His-tagged. For use in Enzyme Assays. Functions as a substrate in ubiquitination assays.
参考价格
8537.29 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Src is a ubiquitously expressed, non-receptor tyrosine kinase that plays a pivotal role in numerous cellular processes such as proliferation, migration, and transformation. Due to its critical function in regulating signal transduction pathways, Src activity is tightly controlled through reversible phosphorylation and dephosphorylation events and down-regulation by ubiquitin-dependent degradation. Dysfunction of Src, through overexpression or increased activation has profound effects on basic cellular functions. Elevated Src expression and/or activation is evident across a wide range of solid tumour types and has been strongly implicated in the development, maintenance, progression, and metastatic spread of several human cancers, such as prostate, lung, breast, and colorectal cancer.

应用

Ubiquitination Cascade Comoponent: Substrate

外形

Purified using immobilized metal affinity chromatography.

其他说明

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160405
NACRESNA.41

产品性质

质量水平300
100
生物来源human
manufacturer/tradenameUpstate®
technique(s)activity assay: suitable
NCBI登记号NM_198291

安全信息

象形图GHS07
警示用语:Warning
危险声明H317
预防措施声明P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
危险分类Skin Sens. 1
储存分类代码10 - Combustible liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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