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c-Kit (V560G) Protein, active, 10 μg

品牌
Sigma-Aldrich
货号
14-730-M
规格纯度
Active, N-terminal GST tagged recombinant human c-Kit, amino acids 544 -end, containing the V560G mutation, found in patients with gastrointestinal stromal tumours. For use in Kinase Assays.
参考价格
7043.46 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Product Source: Human c-Kit (V560G) expressed in Sf21 insect cells.
N-terminal GST tagged recombinant human c-Kit, amino acids 544 - end, containing the V560G mutation. The V560G mutation has been found in patients with gastrointestinal stromal tumours and has been linked to poor prognosis. This mutation confers increased susceptibility to Gleevec.

生化/生理作用

Protein Target: c-Kit
Target Sub-Family: TK

质量

Routinely evaluated by phosphorylation of 250μM GGMEDIYFEFMGGKKK.

外形

Glutathione-agarose
Presented as a frozen solution in 50mM Tris/HCl pH 7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij 35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, and 0.1% 2-mercaptoethanol.

其他说明

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160405
NACRESNA.32

产品性质

质量水平300
100
生物来源human
分子量Mw 76.6 kDa
manufacturer/tradenameUpstate®
technique(s)activity assay: suitable (kinase)
NCBI登记号NM_000222.2
NM_001093772.1
UniProt登记号P10721
Gene Informationhuman ... KIT(3815)

安全信息

象形图GHS07
警示用语:Warning
危险声明H317
预防措施声明P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
危险分类Skin Sens. 1
储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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