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Anti-Leukemia Inhibitory Factor antibody produced in goat

品牌
Sigma-Aldrich
货号
L1044
规格纯度
affinity isolated antibody, lyophilized powder
参考价格
7132.15 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Leukemia inhibitory factor (LIF) is a pleotropic glycoprotein that belongs to the IL6 family of cytokines. It is secreted by many cell types such as, fibroblasts, macrophages, T cells, monocytes, liver cells, osteoblasts and cells of endometrium. LIF interacts with a heterodimeric receptor composed of two subunits, gp130 and gp190. A variety of signal transduction pathways are triggered in response to LIF including ERK/MAPK, JAK1, PI3K, STAT3, Jun-cFos and NF-κB. The various functions of LIF include proliferation of adult human T cells, maintenance of pluripotency of embryonic stem cells and inhibition of leukemic ell differentiation. Reports also indicate the important role of LIF in lactation, tissue regeneration after brain and spinal cord injury, muscle regeneration and motor neuron functions.
Anti-Leukemia Inhibitory Factor recognizes mouse leukemia inhibitory factor. It shows less than 5% cross-reactivity with recombinant human LIF.

免疫原

purified, E. coli-derived recombinant mouse leukemia inhibitory factor.

应用

Anti-Leukemia Inhibitory Factor may be used in neutralization reactions at a working concentration of 0.5 ng/ml. For immunoblotting a concentration of 0.1-0.2 μg/ml is recommended.

外形

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

基本信息

MDL编号MFCD00283185
NACRESNA.41

产品性质

质量水平100
生物来源goat
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式lyophilized powder
species reactivitymouse
technique(s)neutralization: suitable
western blot: 0.1-0.2 μg/mL
UniProt登记号P09056
储存温度−20℃
Gene Informationmouse ... Lif(16878)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)

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