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Luotonin E

品牌
Sigma-Aldrich
CAS
244616-84-0
货号
L4920
规格纯度
≥98%
参考价格
1549.89 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Luotonin E is a heteroaromatic pyrroloquinazolinoquinoline alkaloid that, along with Luotonin A and B, was originally isolated from the Chinese medicinal plant Paganum nigellastrum. Luotonin compounds have antitumor activity and demonstrate cytotoxicity and inhibitory activity against human topoisomerase. For use as a topoisomerase inhibitor, a starting concentration of 25 μM is suggested. It is suggested that a dose-response curve be performed to find the inhibitor concentration most suitable for the intended assay.

包装

10 mg in glass bottle
50 mg in poly bottle

生化/生理作用

Luotonin E exhibited strong cytotoxic effects specifically on human leukemia P-388 cells.

重悬

Solubility is tested at 4 mg/mL in 4:1 solution of choloform and methanol. Solubility of luotonins in DMSO has been reported.

基本信息

线性分子式C19H13N3O2
分子量315.33
NACRESNA.77

产品性质

质量水平200
生物来源synthetic (organic)
测定≥98%
形式solid
溶解性chloroform/methanol (4:1): 4 mg/mL, clear to slightly hazy, colorless to yellow
运输wet ice
储存温度−20℃
Gene Informationhuman ... TOP1(7150)

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P261 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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