产品说明
生化/生理作用
PAK4 (p21 protein (Cdc42/Rac)-activated kinase 4) belongs to the group 2 PAKs, which also include PAK5 and PAK6. Unlike other PAK proteins, PAK4 has strong association with CDC42 (cell division cycle 42) but has weak interaction with RAC (AKT1, v-akt murine thymoma viral oncogene homolog 1). It is a connection between CDC42 and filopodium formation. It regulates CDC42-induced anchorage-independent growth.
外形
Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.
法律信息
PRECISIO is a registered trademark of sigma-aldrich Co. LLC
基本信息
NACRES | NA.32 |
产品性质
质量水平 | 200 |
重组 | expressed in baculovirus infected Sf9 cells |
产品线 | PRECISIO® Kinase |
测定 | ≥70% (SDS-PAGE) |
形式 | buffered aqueous glycerol solution |
specific activity | 61-83 nmol/min·mg |
分子量 | ~90 kDa |
UniProt登记号 | O96013 |
运输 | dry ice |
储存温度 | −70℃ |
Gene Information | human ... PAK4(10298) |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |