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PYK2 (360-690), active, His tagged human

品牌
Sigma-Aldrich
货号
K3768
规格纯度
PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
参考价格
5873.91 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

PYK2 (proline-rich tyrosine kinase 2, also known as FAK2/RAFTK) belongs to the focal adhesion PTK (protein tyrosine kinase) family. It is activated by signals that increases intracellular calcium concentration and also by stress signals. PYK2 is present in the endothelium, central nervous system, and hematopoietic lineages.

生化/生理作用

In osteoclasts, PYK2 (proline-rich tyrosine kinase 2) might be a crucial mediator of integrin αvβ3 signaling events that affects osteoclast physiology as well as pathology. It has a tumor-promoting role in multiple myeloma.

外形

Supplied in 50mM NaPhosphate pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.1mM PMSF, 0.2 mM DTT, 25% glycerol.

法律信息

PRECISIO is a registered trademark of sigma-aldrich Co. LLC

基本信息

NACRESNA.32

产品性质

质量水平200
重组expressed in baculovirus infected Sf9 cells
产品线PRECISIO® Kinase
测定≥70% (SDS-PAGE)
形式buffered aqueous glycerol solution
specific activity216-292 nmol/min·mg
分子量 ~39 kDa
UniProt登记号Q14289
运输dry ice
储存温度−70℃
Gene Informationhuman ... PTK2B(2185)

安全信息

象形图GHS07GHS08
警示用语:Danger
危险声明H315 - H319 - H360D
预防措施声明P202 - P264 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 1
个人防护装备Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

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