位置:首页 > 品牌 > Sigma-Aldrich >

Anti-Potassium Channel K2P4.1 (TRAAK) antibody produced in rabbit

Anti-Potassium Channel K2P4.1 (TRAAK) 兔抗

品牌
Sigma-Aldrich
货号
K0265
规格纯度
affinity isolated antibody, lyophilized powder
参考价格
4915.81 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

The gene K2P4.1, also referred to as KCNK4 (potassium two pore domain channel subfamily K member 4), encodes a protein belonging to the subfamily of K2P (two pore domain K+ channel) channels called TRAAK (TWIK-related arachidonic acid-stimulated K+ channel). The TRAAK channels are expressed selectively in the nervous system. TRAAK channel contains two protomers, each with two distinct pore domains forming a two-fold symmetric potassium channel.

特异性

The K2P4.1 antibody is directed against a highly conserved epitope in the intraracellular C-terminal region of the human K2P4.1 channel.

免疫原

peptide NLAFIDESSDTQSERGC, corresponding to amino acid residues 343-359 of human K2P4.1.

生化/生理作用

The gene KCNK4 (potassium two pore domain channel subfamily K member 4) encodes a potassium channel that is mechanosensitive and is regulated by polyunsaturated fatty acids and temperature. The structure and chemical composition of the lipid bilayer has a profound effect on the functioning of this K+ channel. It is found to regulate the noxious input threshold in dorsal root ganglia neurons.

外形

Lyophilized powder from phosphate buffered saline, pH 7.4, containing 1% BSA and 0.025% sodium azide.

重悬

Reconstitute the lyophilized vial with 50 μL or 200 μL deionized water, depending on package size. Further dilutions should be made using a carrier protein, such as BSA (1-3%).

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD09753858
NACRESNA.41

产品性质

生物来源rabbit
质量水平200
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式lyophilized powder
species reactivityrat, human
technique(s)immunohistochemistry: suitable
western blot: 1:200 using HEK-K2P4.1 transfected cells or rat cerebellum lysate
UniProt登记号Q9NYG8
储存温度−20℃
Gene Informationhuman ... KCNK4(50801)
rat ... Kcnk4(116489)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

推荐产品
| 首页 | 联系我们 | 会员服务 | 广告服务 | 友情链接 |
版权所有 CopyRight © 2008-2024 粤ICP备08119708号