产品说明
一般描述
Angiotensin-converting enzyme (ACE) is a zinc-metallopeptidase belonging to the peptidase M2 family. It catalyzes the conversion of angiotensin I to angiotensin II and the degradation of bradykinin, which increases the vasoconstrictive effects of angiotensin. The Angiotensin-converting enzyme plays an important role in maintaining cardiac function and vascular tone. It is highly expressed in the heart, lung, kidney, gastrointestinal system, and prostate. Defects in the Angiotensin-converting may contribute cardiac disease; and renal tubular dysgenesis, a condition characterized by persistent fetal anuria and perinatal death.
免疫原
Human Angiotensin Converting Enzyme.
应用
Anti-Angiotensin Converting Enzyme Antibody, clone 2E2.
质量
Evaluated by Western Blot in rat Angiotensin Converting Enzyme.
Western Blot Analysis: A 1:2,000 dilution of this antibody detected rat Angiotensin Converting Enzyme in WB.
目标描述
~180 kDa observed. The calculated molecular weight is 150 kDa; however, this protein is known to be glycolsylated.
联系
Replaces: MAB3502
外形
Mouse monoclonal IgG1 cultured supernatant without preservatives.
Unpurified
分析说明
Control
Rat Angiotensin Converting Enzyme
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
产品性质
| 质量水平 | 100 |
| 生物来源 | mouse |
| 抗体形式 | culture supernatant |
| antibody product type | primary antibodies |
| 克隆 | 2E2, monoclonal |
| species reactivity | rat |
| species reactivity (predicted by homology) | human (immunogen homology) |
| technique(s) | western blot: suitable |
| 同位素/亚型 | IgG1 |
| NCBI登记号 | NP_000780 |
| UniProt登记号 | P12821 |
| 运输 | wet ice |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
