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Poly(ethylene glycol) methyl ether-block-poly(D,L lactide)-block-decane

品牌
Sigma-Aldrich
货号
764736
规格纯度
PEG average Mn 2,000, PDLLA average Mn 2,000
参考价格
4438.05 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Block copolymer micelles are widely used in drug delivery applications. PEG-PDLLA is a biodegradable polymeric micelle which is used as a carrier for hydrophobic drugs like Paclitaxel. The hydrophilic PEG and hydrophobic PDLLA form the micelle core wherein the hydrophobic drug is loaded. The incorporation of the 10-alkyl end cap (decane) increases the hydrophobicity of the micelle core and increases its solubilizing capability for hydrophobic drugs.†

应用

Used as a carrier for the controlled and targeted release of anticancer hydrophobic drugs.

包装

1 g in glass bottle

特点和优势

  • Good biocompatibility, low immunogenicity and good degradability.
  • Properties can be easily modulated by changing the block copolymer segment sizes to suit a particular application.

基本信息

NACRESNA.23

产品性质

分子量PDLLA average Mn 2,000
PEG average Mn 2,000
average Mn 4,000 (total)
质量水平100
降解时间线 2-5 weeks
转变温度Tm 29-33 ℃
PDI<1.1 (typical PEG)
<1.2
<1.3 (overall)
储存温度2-8℃

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)230.0 °F
闪点(C)> 110 ℃

Sigma-Aldrich

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