产品介绍：
产品说明
一般描述
Acetylcholine is a neurotransmitter released at nerve endings in both the central and peripheral nervous systems. Acetylcholine chloride (C7H16ClNO2) is a stable cholinergic agonist with muscarinic and nicotinic actions. It is available as white or off-white hygroscopic crystals, or as a crystalline powder. Acetylcholine chloride is hygroscopic in nature and is highly soluble in water, alcohol, propylene glycol and chloroform.
应用
Acetylcholine chloride has been used:
- as an agent to trigger sudomotor axon reflex response during autonomic test
- to induce contraction amplitude of pyloric circular smooth muscle strip (PCSMS) in rats
- as a substrate for acetylcholinesterase
- to stimulate after discharge in Aplysia bag cell neurons
生化/生理作用
氯化乙酰胆碱，20mg/kg体重注射，减少小鼠实验性诱发脓毒病的死亡和血浆促炎细胞因子。类胆碱能抗-炎症机制可能通过乙酰胆碱和 α7n单核细胞，巨噬细胞和中性粒细胞上的胆红素受体互作接待，降低了促炎细胞活素，比如 TNF-α,IL-1β,和IL-6。
注意
非常吸湿
法律信息
Redi-Dri is a trademark of sigma-aldrich Co. LLC
基本信息
| 线性分子式 | (CH3)3N+CH2CH2OCOCH3Cl- |
| 分子量 | 181.66 |
| Beilstein | 3571875 |
| MDL编号 | MFCD00011698 |
产品性质
| 产品线 | Redi-Dri™ |
| 质量水平 | 100 |
| 测定 | ≥99% (TLC) |
| 质量 | free-flowing |
| mp | 146-150 ℃ (lit.) |
| 溶解性 | H2O: 100 mg/mL |
| SMILES string | [Cl-].CC(=O)OCC[N+](C)(C)C |
| InChI | 1S/C7H16NO2.ClH/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1 |
| InChI key | JUGOREOARAHOCO-UHFFFAOYSA-M |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
