产品说明
一般描述
Pancreatic α-amylase is produced by the pancreatic acinar cells and released into the duodenum. It is a major molecule of pancreatic fluid.
应用
α-Amylase from hog pancreas has been used:
- in the in vitro digestion system to study the hydrolysis of pea globulins
- in vitro α-amylase inhibition study
- to prepare digestive juice (salivary juice) for the in vitro model of the human digestion system
生化/生理作用
α-Amylase is a starch hydrolase, for glucose production, important for energy acquisition. It catalyzes the hydrolysis of α-1,4-glycosidic linkages in starch to form glucose, maltose, and maltotriose units. In mammals, α-amylase regulates the sugar assimilation by reducing the glucose uptake by Na+/glucose cotransporter 1 (SGLT1) and stimulating glycoprotein N-glycans mediated starch digestion. α-Amylase inhibitors are associated with the treatment of type 2 diabetes mellitus. α-Amylases are widely known industrial enzymes used in food, detergent, textile, fermentation, and pharmaceutical industries.
单位定义
1单位酶相当于在pH 6.9和25℃条件下,每分钟释放1 μmol麦芽糖所需的酶量(淀粉符合Zulkowsky,货号85642,作为底物)
其他说明
最佳酸碱度和温度分别为6.9和53℃;钙是活性所必需的,也能防止胰蛋白酶降解;表征。
基本信息
EC 号 | 232-565-6 |
NACRES | NA.54 |
产品性质
形式 | powder |
质量水平 | 100 |
specific activity | ~50 U/mg |
储存温度 | 2-8℃ |
安全信息
象形图 | |
警示用语: | Danger |
危险声明 | H334 |
预防措施声明 | P261 - P342 + P311 |
危险分类 | Resp. Sens. 1 |
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |