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Monoclonal Anti-Granulocyte Colony Stimulating Factor antibody produced in rat

品牌
Sigma-Aldrich
货号
G5421
规格纯度
clone 67604, purified immunoglobulin, lyophilized powder
参考价格
4731.57 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Mature myeloid cells are derived from bone-marrow derived precursor cells by the activity of three colony stimulating factors, granulocyte/macrophage colony-stimulating factor (GM-CSF), macrophage colony-stimulating factor (M-CSF) and granulocyte colony-stimulating factor (G-CSF). The expression of G-CSF is the result of activation of pathways in response to tumor necrosis factor-α, LPS and toll-like receptor ligands. The pathways that induce the effects of G-CSF are PI3K, ERK1/2 and p38. The generation of neutrophils and induction of the circulation of hematopoietic stem cells from the bone marrow are the main functions of G-CSF. There are additional activities attributed to G-CSF such as neuroprotection, immunomodulation and generation of cardiac cells and dendritic cells. Large quantities of G-CSF are secreted in a variety of myeloid and non-myeloid cancers and rheumatoid arthritis
Monoclonal anti-granulocyte colony stimulating factor recognizes mouse G-CSF. The antibody shows less than 0.06% cross-reactivity with recombinant human G-CSF.

免疫原

purified, recombinant mouse granulocyte colony stimulating factor, expressed in E. coli.

应用

Anti-granulocyte colony stimulating factor antibody may be used for immunoblotting at a working concentration of 1-2 μg/ml. For ELISA the recommended concentration range is 2-8 μg/ml. The antibody is also suitable for neutralization assays.

外形

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

质量水平100
生物来源rat
偶联物unconjugated
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆67604, monoclonal
形式lyophilized powder
species reactivitymouse
technique(s)capture ELISA: 2-8 μg/mL
neutralization: suitable
western blot: 1-2 μg/mL
同位素/亚型IgG1
UniProt登记号P09920
储存温度−20℃
Gene Informationmouse ... Csf3(12985)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)

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