产品介绍：
产品说明
应用
GR 103691 has been used as a D3 receptor antagonist to test its:
- inducing effect on prepulse inhibition (PPI)
- suppressive effect of motor behavior in rats
- inhibitory effect on chemotaxis in newly excysted juvenile C. sinensis (CsNEJs)
包装
10 mg in glass bottle
生化/生理作用
GR 103691 increases the monosynaptic “stretch” reflex (MSR) amplitude in mice by its potent D3 receptor antagonist functionality. It inhibits the PD 128,907 mediated γ-aminobutyric acid (GABA) release.
D3 dopamine receptor antagonist.
特点和优势
This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
法律信息
Sold for research purposes under agreement from GlaxoSmithKline
基本信息
| 经验(实验)分子式 | C30H35N3O3 |
| 分子量 | 485.62 |
| MDL编号 | MFCD00936840 |
| PubChem化学物质编号 | 24724488 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | solid |
| 颜色 | white |
| 溶解性 | DMSO: soluble >5 mg/mL at 60 ℃ |
| 创始人 | GlaxoSmithKline |
| 储存温度 | 2-8℃ |
| SMILES string | COc1ccccc1N2CCN(CCCCNC(=O)c3ccc(cc3)-c4ccc(cc4)C(C)=O)CC2 |
| InChI | 1S/C30H35N3O3/c1-23(34)24-9-11-25(12-10-24)26-13-15-27(16-14-26)30(35)31-17-5-6-18-32-19-21-33(22-20-32)28-7-3-4-8-29(28)36-2/h3-4,7-16H,5-6,17-22H2,1-2H3,(H,31,35) |
| InChI key | JARNORYOPMINDY-UHFFFAOYSA-N |
| Gene Information | rat ... Htr1a(24473) |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
