产品说明

一般描述

Cholesterol Esterase is a serine hydrolase released from the exocrine pancreas. It belongs to the α/β hydrolase family of enzymes.

应用

Cholesterol Esterase from porcine pancreas has been used:

• in an in vitro simulated digestion model to improve the hydrolysis of carotenoid esters in the intestinal phase
• to analyze the bioavailability of phytosterol and cholesterol in the aqueous micellar phase of an in vitro simulated digestion model
• as a standard in enzyme activity assay

生化/生理作用

For the hydrolysis of cholesterol esters in the determination of total cholesterol in serum or plasma; Application in (selective) hydrolysis/condensation of carboxylic ester bonds
Cholesterol esterase exhibits broad substrate specificity and regulates the bile salt-mediated hydrolysis of dietary cholesteryl esters. It participates in the hydrolysis of triglycerides and phospholipids which are essential for normal cholesterol absorption. Cholesterol esterase plays a key role in transporting free cholesterol to enterocytes. Loss of enzyme function reduces the intestinal absorption of dietary cholesteryl esters.

单位定义

1 U相当于在pH 7.0和37℃下每分钟释放1μmol胆固醇的酶的量(乙酸胆固醇为底物)。

其他说明

可能适用相应的销售限制

基本信息

产品性质

安全信息