Anti-Rev antibody produced in chicken

产品说明

一般描述

Rev is a regulatory protein of human immunodeficiency virus type 1. It consists of a hydrophobic core, which is formed by binding to another REV molecule and arginine-rich motifs (ARMs).

免疫原

Immunogen Sequence: GI # 12831140, sequence 1-116
Recombinant Rev protein (HIV-1 vector pNL4-3)

应用

Anti-Rev antibody produced in chicken is suitable for western blotting at a working dilution of 1:500 and for cell staining at a working dilution of 1:200.

生化/生理作用

Rev is involved in the stabilization and transport of the viral mRNA. It is involved in the up-regulation of the gag- and env-producing mRNAs via cis-acting element in the env region of HIV-1, named rev responsive element. It increases the stability of the unspliced viral mRNA and promotes the transport of the viral mRNA having the rev-responsive element from the nucleus to the cytoplasm.

外形

Solution in phosphate buffered saline containing 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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