Anti-C1QA antibody produced in chicken

产品说明

免疫原

Complement C1q subcomponent subunit A native protein.
Immunogen Sequence: GI # 7705753, sequence 1-245

应用

Anti-C1QA antibody produced in chicken is suitable for indirect ELISA and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生化/生理作用

Complement C1q subcomponent subunit A is a protein encoded by the C1QA gene in humans. Anti-C1q antibodies are found to be pathogenic in the target organ damage of many autoimmune diseases, by facilitating C1q deposition and enhancing complement activation through classical pathway. It is also found to be associated with glomerular basement membrane (GBM) disease and in the pathogenesis of lupus. C1q deficiency leads to the development of autoimmune pathology throughout the life. C1q-binding protein participates in C1q-mediated chemotaxis of blood immune cells.

外形

Solution in phosphate buffered saline containing 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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