产品说明
一般描述
Epidermal keratinocytes comprise 90 % of all cells found in the epidermis, the outermost layer of skin. They produce keratin, the intermediate filament, largely responsible for skin′s barrier function. Through their interactions with epidermal melanocytes, keratinocytes obtain melanin and store it as a means of protection from UV radiation.
HEK provide an excellent model system to study many aspects of epithelial function and disease, particularly those related to skin biology and toxicology, as well as HPV infection.
When grown on inserts and provided with the liquid/air interface, HEK can differentiate into a stratified squamous epithelium and serve as a more physiological 3D tissue model for in vitro studies.
细胞系来源
Skin
应用
Skin biology and toxicology, wound healing, artificial skin, cell proliferation, migration, UV light response
组分
Basal Medium containing 10% FBS & 10% DMSO
制备说明
- Primary culture, >500,000 cells in Basal Medium containing 10% FBS & 10% DMSO
- Can be cultured at least 16 doublings
传代培养常规
Please refer to the HEK Culture Protocol.
基本信息
| NACRES | NA.81 |
产品性质
| 质量水平 | 100 |
| 生物来源 | human neonatal foreskin or adult skin (normal) |
| 包装 | pkg of 500,000 cells |
| 生长模式 | Adherent |
| 核型 | 2n = 46 |
| 形态学 | Epidermal |
| technique(s) | cell culture | mammalian: suitable |
| 相关疾病 | allergies; cancer |
| 运输 | dry ice |
| 储存温度 | −196℃ |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
