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Prostaglandin F Synthase human

品牌
Sigma-Aldrich
CAS
55976-95-9
货号
F7807
规格纯度
recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
参考价格
5580.84 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

应用

Prostaglandin F synthase (PGF synthase) is a member of the aldo-keto reductase superfamily of proteins which catalyze the conversion of aldehydes and ketones to thier corresponding alcohols. Prostaglandin F synthase is used in cancer research since it is upregulated in many cancers such as breast and prostate cancer. PGF synthase is also used to study kidney and renal cell carcinoma .

生化/生理作用

PGF synthase catalyzes the conversions of 4-androstene-3,17-dione to testosterone, estrone to 17β-estradiol, prostaglandin H2 to PGF2α, and PGD2 to 9α,11β-PGF2. Prostaglandin (PG) F2 is synthesized via three pathways .

单位定义

One unit is defined as the amount of enzyme required to produce 1 μmol of NADP per minute at 37℃ in 50 mM KPO4 pH 7.2 containing 250 μM NADPH and 25 μM 9,10-phenanthrenequinone

基本信息

酶学委员会(EC)编号1.1.1.188 ( BRENDA | IUBMB )
NACRESNA.54

产品性质

质量水平200
重组expressed in E. coli
描述contains a C-terminal hexahistidine tag
测定≥90% (SDS-PAGE)
形式liquid
specific activity≥0.4 μmol/mg protein
分子量 ~37 kDa
NCBI登记号NP_003730
运输dry ice
储存温度−70℃
Gene Informationhuman ... AKR1C3(8644)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

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