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Etidronate disodium hydrate

依替膦酸钠 二钠 水合物

品牌
Sigma-Aldrich
CAS
7414-83-7
货号
P5248
规格纯度
≥97% (NMR), solid
参考价格
1156.54 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

应用

Etidronate disodium hydrate has been used in the synthesis of bisphosphonate derivatives of adenosine triphosphate (ATP)by T4 RNA ligase. It has also been sued to inhibit human farnesyl diphosphate synthase (FDPS).

包装

10, 100 mg in glass bottle

生化/生理作用

Etidronate helps to guard chronic ocular hypertension prompted retinal oxidative stress. It stimulates the development of retinal ganglion cells through insulin-like growth factor 1 (IGF-1) signaling pathway. It may possess neuroprotective effects in in vivo and in vitro rat model of glaucoma. Etidronate belongs to bisphosphonates.
Bisphosphonate antiresorptive agent. Less potent inhibitor of farnesyl diphosphate synthase (IC50 = 80 μM) as compared to the nitrogen containing bisphosphonates

基本信息

经验(实验)分子式C2H6Na2O7P2 · xH2O
分子量249.99 (anhydrous basis)
EC 号231-025-7
MDL编号MFCD00152567
PubChem化学物质编号329820220
NACRESNA.77

产品性质

质量水平100
测定≥97% (NMR)
形式solid
颜色 white
mp>300 ℃
溶解性H2O: ≥10 mg/mL
储存温度2-8℃
SMILES string[Na+].[Na+].CC(O)(P(O)([O-])=O)P(O)([O-])=O
InChI1S/C2H8O7P2.2Na/c1-2(3,10(4,5)6)11(7,8)9;;/h3H,1H3,(H2,4,5,6)(H2,7,8,9);;/q;2*+1/p-2
InChI keyGWBBVOVXJZATQQ-UHFFFAOYSA-L

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
危险分类Acute Tox. 4 Oral
储存分类代码13 - Non Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves

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