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PDGFRα (550-end), active, GST tagged human

品牌
Sigma-Aldrich
货号
D0946
规格纯度
PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
参考价格
6429.69 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

生化/生理作用

PDGFRα (platelet-derived growth factor receptor α) is a member of the PDGFR family of membrane receptors with intrinsic tyrosine kinase activity. Aberrant expression of PDGFRα has been linked to developmental abnormalities in vertebrate models and has been implicated in multiple disease states in humans. There is widespread expression of PDGFRα in renal cell types involved in fibrotic and sclerosing processes. PDGF and its receptor PDGFRα are inducers of fibrosis in the repair phase of inflammatory bowel disease and they may also be involved in the active inflammatory phase.

外形

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

法律信息

PRECISIO is a registered trademark of sigma-aldrich Co. LLC

基本信息

NACRESNA.32

产品性质

质量水平200
重组expressed in baculovirus infected Sf9 cells
产品线PRECISIO® Kinase
测定≥70% (SDS-PAGE)
形式buffered aqueous glycerol solution
specific activity10-14 nmol/min·mg
分子量 ~95 kDa
UniProt登记号P16234
运输dry ice
储存温度−70℃
Gene Informationhuman ... PDGFRA(5156)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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