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Dipeptidyl Peptidase VII human

品牌
Sigma-Aldrich
货号
D3321
规格纯度
recombinant, expressed in Sf9 cells
参考价格
7847.25 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

应用

Dipeptidyl Peptidase VII (DPP7), also known as DPP2 or quiescent cell proline dipeptidase, is a post-proline cleaving aminopeptidase that is expressed in quiescent lymphocytes . DPP7 is used to study the regulation of cell quiescence . Like DPP4, DPP7 may be useful in diabetes and vascular disease research .

生化/生理作用

DPP7 is essential for maintaining lymphocytes and fibroblasts in G(0). The inhibition of DPP7 results in apoptosis, which is mediated by the induction of c-Myc and p53 . DPP7 has strong sequence homology with prolylcarboxypeptidase and is active at both acidic and neutral pH.

物理属性

Contains amino acids 29 to end with a C-terminal His tag, MW=89.1 kDa

单位定义

One unit will hydrolyze 1.0 picomole of Ala-Pro-AMC per minute at pH 7.4 at 25 deg ℃

外形

Supplied as a solution in 25 mM Tris-HCl, pH 8.0, 130 mM NaCl, 0.05% Tween-20, 10% glycerol

基本信息

酶学委员会(EC)编号3.4.14.-
NACRESNA.54

产品性质

质量水平200
重组expressed in Sf9 cells
形式solution
specific activity≥1,500 units/μg protein
≥1500 units/μg protein
分子量 89.1 kDa
相关疾病diabetes; cardiovascular diseases
运输dry ice
储存温度−70℃

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

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