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Alosetron Hydrochloride

品牌
Sigma-Aldrich
CAS
122852-69-1
货号
SML0346
规格纯度
≥98% (HPLC)
参考价格
730.94 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

包装

10, 50 mg in glass bottle

生化/生理作用

Alosetron is a potent and highly selective antagonist of serotonin 5-HT3 receptors, nonselective cation channels found predominantly in the enteric nervous system of the gastrointestinal tract. These receptors are involved in the regulation of visceral pain, colonic transit and GI secretions that can contribute to the pathophysiology of irritable bowel syndrome (IBS). Alosetron is used clinically for treatment of women with severe diarrhea-predominant IBS.

基本信息

经验(实验)分子式C17H18N4O·HCl
分子量330.81
MDL编号MFCD09028027
PubChem化学物质编号329825350
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
储存条件desiccated
颜色 white to beige
溶解性H2O: ≥5 mg/mL at warmed
储存温度2-8℃
SMILES stringCN1C2=C(C=CC=C2)C3=C1CCN(CC4=C(C)N=CN4)C3=O.Cl
InChI1S/C17H18N4O.ClH/c1-11-13(19-10-18-11)9-21-8-7-15-16(17(21)22)12-5-3-4-6-14(12)20(15)2;/h3-6,10H,7-9H2,1-2H3,(H,18,19);1H
InChI keyFNYQZOVOVDSGJH-UHFFFAOYSA-N
Gene Informationhuman ... HTR3A(3359)

安全信息

象形图GHS06
警示用语:Danger
危险声明H301 - H319 - H412
预防措施声明P273 - P301 + P310 + P330 - P305 + P351 + P338
危险分类Acute Tox. 3 Oral - Aquatic Chronic 3 - Eye Irrit. 2
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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