产品说明
一般描述
18:1 Diether PC (phosphocholine) is a class of glycerophospholipids that has two octadecene chains attached to the sn-1 and sn-2 positions of the glycerol backbone by ether bonds. It has choline as the alcohol moiety, attached to the phosphate group.
应用
18:1 Diether PC or 1,2-di-O-(9Z-octadecenyl)-sn-glycero-3-phosphocholine might be used:
- to prepare proteoliposomes to investigate the effects of ceramide and ceramide phosphate/ for the determination of phospholipase A activity of lecithin-cholesterol acyltransferase (LCAT) in the ether matrix
- to prepare lipid bilayer membrane to study the influence of glutamic acid residues and pH on the properties of transmembrane helices
- in large unilamellar vesicles (LUVs) to explore the differential interaction of pH (low) insertion peptide (pHLIP) with it by utilizing fluorescence and circular dichroism (CD) spectroscopic approaches
生化/生理作用
Lipids prepared using 18:1 Diether PC (phosphocholine), are found to be more stable than the natural ester lipids under alkaline conditions.
包装
5 mL Clear Glass Sealed Ampule (999989C-10mg)
基本信息
经验(实验)分子式 | C44H88NO6P |
分子量 | 758.15 |
NACRES | NA.25 |
产品性质
包装 | pkg of 1 × 1 mL (999989C-10mg) |
manufacturer/tradename | Avanti Polar Lipids 999989C |
浓度 | 10 mg/mL (999989C-10mg) |
运输 | dry ice |
储存温度 | −20℃ |
SMILES string | [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OCCCCCCCC/C=C\CCCCCCCC)COCCCCCCCC/C=C\CCCCCCCC)=O |
安全信息
象形图 | |
警示用语: | Danger |
危险声明 | H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 - H412 |
预防措施声明 | P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313 |
危险分类 | Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3 |
靶器官 | Central nervous system |
储存分类代码 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
WGK | WGK 3 |
闪点(F) | does not flash |
闪点(C) | does not flash |