Anti-CFTR antibody produced in rabbit

产品说明

一般描述

CFTR (Cystic fibrosis transmembrane conductance regulator, ATP-binding cassette sub-family C, member 7) is a membrane-associated, N-linked glycoprotein.

免疫原

synthetic peptide corresponding to amino acids 103-117 of human CFTR protein. The sequence is 100% conserved in human, rabbit, and monkey. There is a one amino acid substitution in rat, bovine, and sheep.

应用

Anti-CFTR antibody produced in rabbit is suitable for immunocytochemistry at a concentration of 1μg/mL using HEK293 cells overexpressing human CFTR.

生化/生理作用

Cystic fibrosis transmembrane conductance regulator (CFTR) gene is associated with congenital bilateral absence of the vas deferens (CBAVD) and causes the genital form of cystic fibrosis (CF). The CFTR gene may also be involved in the etiology of male infertility. It may be useful for assisting reproduction technology. There is nearly 2000 cystic fibrosis transmembrane regulator (CFTR) mutations that are associated with cystic fibrosis (CF).

外形

Solution in phosphate buffered saline containing 1.0 mg/mL bovine serum albumin and 0.05 % sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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