产品说明
一般描述
NLR family CARD domain-containing protein 4 is a protein encoded by NLRC4 gene in humans. NLRC4 is also known as CLAN, IPAF, CLAN1, CLANA, CLANB, CLANC, CLAND, CARD12 and CLR2. It is a member of the Ced4/ Apaf-1 family.
免疫原
peptide corresponding to the N-terminus of the human CLAN protein, both A and B isoforms.
应用
Anti-CLAN Protein (CARD12) antibody produced in rabbit is suitable for western blotting at a dilution of 1:500-1:1,000 using human lung lysates.
生化/生理作用
CLAN (CARD12) induces apoptosis and plays a critical role in NF-κB signaling pathways. CARD12 plays an important role during activation of caspase-1 and is dependent on the nucleotide-binding site. It prevents motor-neuron apoptosis induced by a variety of signals.
外形
Solution of 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD08705448 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 200 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen ~116 kDa (CLAN-A) antigen ~40 kDa (CLAN-B) |
| species reactivity | human |
| technique(s) | western blot: 1:500-1:1,000 using lung lysates |
| UniProt登记号 | Q9NPP4 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... NLRC4(58484) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
