产品说明
免疫原
purified recombinant human CD40 ligand C-terminal extracellular domain, expressed in E. coli.
应用
Anti-CD40 Ligand antibody produced in goat is suitable for flow cytometry and western blotting at a concentration of 1μg/mL.
生化/生理作用
CD40 Ligand is a protein that is primarily expressed on activated T cells and belongs to the TNF superfamily of molecules. It binds to CD40 on antigen-presenting cells (APC). The expression and primary function of the cell surface receptor CD40 and its ligand CD154 were not only restricted to B and T lymphocytes, but is also associated with pathogenic processes of chronic inflammatory diseases, such as autoimmune diseases, neurodegenerative disorders, graft-versus-host disease, cancer and atherosclerosis. Over expression of CD40 Ligand (sCD40L) were found in serum but not in plasma of patients with chronic spontaneous urticaria (CU).
外形
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD01094428 |
| NACRES | NA.41 |
产品性质
| 质量水平 | 100 |
| 生物来源 | goat |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | lyophilized powder |
| species reactivity | human |
| technique(s) | flow cytometry: suitable (2.5 μg/106 cells using treated human peripheral blood mononuclear cells) western blot: 1 μg/mL |
| UniProt登记号 | P29965 |
| 储存温度 | −20℃ |
| Gene Information | human ... CD40LG(959) |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
