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Anti-Calcium Channel (γ4 Subunit) (Voltage Gated Ca2+ Channel) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
C6363
规格纯度
~1 mg/mL, buffered aqueous solution, fractionated antiserum
参考价格
4330.86 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

特异性

Specifically recognizes a splice variant of γ4 (36.5 kDa) from human, mouse and rat.

免疫原

synthetic peptide derived from the rat γ4 calcium channel subunit conjugated to KLH.

应用

Anti-Calcium Channel (γ4 Subunit) (Voltage Gated Ca2+ Channel) antibody produced in rabbit is suitable for western blotting at a concentration of 5-10μg/mL using rat brain tissue lysate.

生化/生理作用

Voltage-dependent calcium channel γ-4 subunit is a protein encoded by the CACNG4 gene in humans and the three novel Ca2+ channel γ subunit genes (CACNG3, CACNG4, and CACNG5) are mapped on chromosome 16 and 17. It is a transmembrane protein that may act as both neuronal voltage-dependent calcium channel (VDCC) γ subunits and transmembrane α-amino-3-hydroxy-5-methyl-4-isoxazoleproponinc (AMPA) receptor regulatory proteins (TARPs). CACNG4 is found to be expressed in the CNS and display differential distributions among brain regions and several cell types in found in the cerebellum and hippocampus. It plays a key role in VDCC function. CACNG4 function as regulators of AMPA receptor localization and function in the brain and are collectively known as TARPs.

外形

Phosphate buffered saline containing 0.08% sodium azide.

基本信息

MDL编号MFCD06201927
NACRESNA.41

产品性质

生物来源rabbit
质量水平200
偶联物unconjugated
抗体形式fractionated antiserum
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
species reactivitymouse, rat, human
浓度~1 mg/mL
technique(s)western blot: 5-10 μg/mL using rat brain tissue lysate
UniProt登记号Q9UBN1
运输wet ice
储存温度−20℃
Gene Informationhuman ... CACNG4(27092)
mouse ... Cacng4(54377)
rat ... Cacng4(140725)

Sigma-Aldrich

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