S-(-)-Carbidopa

产品介绍：

产品说明

一般描述

Carbidopa is used for treating restless legs (RL) syndrome and periodic leg movements in sleep (PLMS). Carbidopa along with levodopa is used to treat Parkinson′s disease.

包装

25 mg in poly bottle
100 mg in glass bottle

生化/生理作用

Peripheral inhibitor of L-aromatic amino acid decarboxylase. When co-administered with L-DOPA, it prevents extra-CNS conversion to dopamine, thereby increasing CNS concentrations of effective compounds. Selectively cytotoxic to human pulmonary carcinoid and small cell lung carcinoma cells by increasing H₂O₂ in these cell lines, which are sensitive to reactive oxygen species.

基本信息

经验(实验)分子式	C₁₀H₁₄N₂O₄
分子量	226.23
EC 号	249-271-9
MDL编号	MFCD00069231
PubChem化学物质编号	24892402
NACRES	NA.77

产品性质

质量水平	200
测定	≥98% (TLC)
形式	powder
溶解性	methanol and 1 drop HCl: 4.90-5.10 mg/mL, clear, colorless to faintly yellow
储存温度	−20℃
SMILES string	CC(Cc1ccc(O)c(O)c1)(NN)C(O)=O
InChI	1S/C10H14N2O4/c1-10(12-11,9(15)16)5-6-2-3-7(13)8(14)4-6/h2-4,12-14H,5,11H2,1H3,(H,15,16)/t10-/m0/s1
InChI key	TZFNLOMSOLWIDK-JTQLQIEISA-N
Gene Information	human ... DDC(1644)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)