产品说明
一般描述
1,2-dioleoyl-sn-glycero-3-ethylphosphocholine (18:1 EPC) is a cationic alkylated phospholipid.
应用
1,2-dioleoyl-sn-glycero-3-ethylphosphocholine (chloride salt) (18:1 EPC (Cl Salt)) is suitable:
- for composing lipid shell to prepare lipopolyplex/mRNA vaccine
- in solvent-assisted preparation of supported lipid bilayers
- along with 1,2-dioleoyl-sn-glycero-3-phosphatidylethanolamine (DOPE) in mixed liposomes as colloidal vectors for physicochemical study of the DNA compaction
- to formulate the lipid nanoparticle (LNP1) to enhance intracellular delivery mediated by shock waves
生化/生理作用
1,2-dioleoyl-sn-glycero-3-ethylphosphocholine (18:1 EPC) serves as a transfection reagent. 18:1 EPC is applicable in liposomes and lipoplexes. It is a potential vector in gene therapy.
包装
5 mL Clear Glass Sealed Ampule (890704C-100mg)
5 mL Clear Glass Sealed Ampule (890704C-25mg)
5 mL Clear Glass Sealed Ampule (890704C-200mg)
基本信息
经验(实验)分子式 | C46H89NO8PCl |
分子量 | 850.63 |
NACRES | NA.25 |
产品性质
包装 | pkg of 1 × 2.5 mL (890704C-25mg) pkg of 1 × 4 mL (890704C-100mg) pkg of 2 × 4 mL (890704C-200mg) |
manufacturer/tradename | Avanti Polar Lipids 890704C |
浓度 | 10 mg/mL (890704C-25mg) 25 mg/mL (890704C-100mg) 25 mg/mL (890704C-200mg) |
运输 | dry ice |
储存温度 | −20℃ |
SMILES string | O=P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O)OCC.[Cl-] |
安全信息
象形图 | |
警示用语: | Danger |
危险声明 | H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 - H412 |
预防措施声明 | P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313 |
危险分类 | Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3 |
靶器官 | Central nervous system |
储存分类代码 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
WGK | WGK 3 |
闪点(F) | does not flash |
闪点(C) | does not flash |