产品说明
一般描述
Terazosin hydrochloride is used to treat hypertension and benign prostatic hyperplasia (BPH). It is metabolised in the liver. It might be associated with dizziness, headache and asthenia. Terazosin hydrochloride is linked to acute generalized exanthematous pustulosis.
应用
Terazosin hydrochloride has been used for orthogonality and similarity analysis using reversed-phase chromatographic studies5. Furthermore, terazosin has also been used for the evaluation of chemometric techniques to determine orthogonality and similarity in chromatographic methods6.
包装
250 mg in glass bottle
50 mg in poly bottle
生化/生理作用
α1-adrenoceptor antagonist.
特点和优势
This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
制备说明
Terazosin hydrochloride is soluble in water at 19.60 - 20.40 mg/ml and yields a clear, colorless to faint yellow solution. It is also soluble in ethanol at 4 mg/ml. Furthermore, the product is soluble in methanol at 20 mg/ml, with heat as needed, and yields a clear, colorless solution.
基本信息
| 经验(实验)分子式 | C19H25N5O4 · HCl |
| 分子量 | 423.89 |
| MDL编号 | MFCD00467965 |
| PubChem化学物质编号 | 24278740 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 200 |
| 测定 | ≥98% (TLC) |
| 形式 | powder |
| 颜色 | white to off-white |
| 溶解性 | H2O: soluble 19.60-20.40 mg/mL, clear, colorless to faintly yellow methanol: 20 mg/mL, clear, colorless ethanol: 4 mg/mL |
| 创始人 | Abbott |
| SMILES string | Cl[H].COc1cc2nc(nc(N)c2cc1OC)N3CCN(CC3)C(=O)C4CCCO4 |
| InChI | 1S/C19H25N5O4.ClH/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14;/h10-11,14H,3-9H2,1-2H3,(H2,20,21,22);1H |
| InChI key | IWSWDOUXSCRCKW-UHFFFAOYSA-N |
| Gene Information | human ... ADRA1A(148), ADRA1B(147), ADRA1D(146) |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H302 |
| 预防措施声明 | P264 - P270 - P301 + P312 - P501 |
| 危险分类 | Acute Tox. 4 Oral |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
