产品说明
应用
Desloratadine has been used to test its effect on embryoid body development in in vitro gastrulation model of P19C5 stem cells. It has also been used as an antihistamine mimic in rats and to treat lung cancer (A549) and glioblastoma (U87) cells in various cellular studies.
包装
10, 50 mg in glass bottle
生化/生理作用
Desloratadine is a selective and nonsedating histamine H1 receptor antagonist, an active metabolite of loratadine (Claritin), used to relieve hay fever and allergy symptoms with less drowsiness than other antihistamines; does not significantly inhibits cardiac K+ channels at clinically achievable blood levels. Free from antimuscarinic/anticholinergic effects.
其他说明
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. D1069.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
法律信息
Clarinex is a registered trademark of Schering Corp.
基本信息
| 经验(实验)分子式 | C19H19ClN2 |
| 分子量 | 310.82 |
| MDL编号 | MFCD00871949 |
| PubChem化学物质编号 | 329798668 |
| NACRES | NA.32 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 溶解性 | DMSO: >10 mg/mL |
| 储存温度 | 2-8℃ |
| SMILES string | Clc1ccc2c(CCc3cccnc3\C2=C4\CCNCC4)c1 |
| InChI | 1S/C19H19ClN2/c20-16-5-6-17-15(12-16)4-3-14-2-1-9-22-19(14)18(17)13-7-10-21-11-8-13/h1-2,5-6,9,12,21H,3-4,7-8,10-11H2 |
| InChI key | JAUOIFJMECXRGI-UHFFFAOYSA-N |
| Gene Information | human ... HRH1(3269) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
