产品说明
一般描述
XPOT (exportin T) is a tRNA nuclear export receptor found in vertebrates. This protein shuttles between the cytoplasm and nucleus. It belongs to the importin-β family, and has a distant relation to Los1p protein found in yeast.
免疫原
Immunogen Sequence: GI # 8051636, sequence 5-234
Recombinant TRNA exportin
应用
Anti-Exportin T antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
生化/生理作用
Exportin-T acts as a specific mediator of tRNA export. Exportin-T is a RanGTP-binding, importin β-related factor with predominantly nuclear localization that shuttles rapidly between nucleus and cytoplasm. It interacts with nuclear pore complexes as well. Exportin-t binds tRNA directly and with high affinity. It is responsible for majority of tRNA export in cells and plays an essential role in the transport of tRNA. It is associated with intracellular tRNA trafficking and is in turn associated with discrete changes in the composition of cellular cytoplasmic multi-protein complexes containing tRNA.
外形
Solution in phosphate buffered saline containing 0.02% sodium azide.
基本信息
| MDL编号 | MFCD03454996 |
产品性质
| 生物来源 | chicken |
| 质量水平 | 200 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| species reactivity | human |
| manufacturer/tradename | Genway 15-288-21255B |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_009166.2 |
| UniProt登记号 | O43592 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... XPOT(11260) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
