Anti-ADFP (ab2) antibody produced in chicken

产品说明

一般描述

ADFP (adipose differentiation-related protein) is a mammalian lipid droplet protein, which coats lipid droplet surfaces. It is however absent from mature white adipocytes. It is also called perilipin 2 (PLIN2), and is a member of the PAT (perilipin, adipophilin, and the tail-interacting protein 47kDa) family of proteins, which includes five members. It has a predominant expression in skeletal muscles, in type I fibres.

免疫原

Immunogen Sequence: GI # 34577059, sequence 241-437
Recombinant adipose differentiation-related protein

应用

Anti-ADFP (ab2) antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生化/生理作用

Adipose differentiation-related protein (ADFP) plays a novel role in the regulation of macrophage autophagy during lipopolysaccharide (LPS) stimulation. ADFP is the most abundant lipid droplet (LD)-associated protein found in non-adipose tissue and its expression correlates with intracellular lipid accumulation. Its polymorphism may affect its function and influence the development of metabolic and cardiovascular diseases. It has been observed that prolonged endurance-type exercise training increases the expression of ADFP leading to increases in intramuscular triglyceride (IMTG) content in a type I muscle fiber-type specific manner in type 2 diabetes patients.

外形

Solution in phosphate buffered saline containing 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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