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14-3-3 Beta histidine-tagged human

品牌
Sigma-Aldrich
货号
B6312
规格纯度
recombinant, expressed in E. coli, ≥90% (SDS-PAGE), buffered aqueous glycerol solution
参考价格
7712.1 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

生化/生理作用

14-3-3 proteins are a multifunctional protein family comprising seven mammalian isoforms that interact with over two hundred different intracellular molecules including kinases, phosphatases, transcription factors, scaffold proteins, and DNA. 14-3-3 proteins are involved in a multitude of biological functions and play a regulatory role in processes such as apoptotic cell death, mitogenic signal transduction, and cell cycle control. 14-3-3 β participates in various processes, among which is the positive regulation of cell cycle progression and tumorigenesis. Over-expression of 14-3-3 β in NIH-3T3 cells confers tumorigenicity in nude mice via activation of the mitogen-activated protein kinase (MAPK) cascade.

外形

Supplied as a 0.2 μm filtered solution in 50 mM Tris, pH 7.6, 1 mM EDTA, 1 mM DTT and 20% glycerol (w/v).

基本信息

NACRESNA.32

产品性质

质量水平200
重组expressed in E. coli
测定≥90% (SDS-PAGE)
形式buffered aqueous glycerol solution
UniProt登记号P31946
运输dry ice
储存温度−20℃
Gene Informationhuman ... YWHAB(7529)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

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