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Clemastine fumarate salt

(+)-2-[2-[(p-Chloro-α-methyl-α-phenylbenzyl)oxy]ethyl]-1-methylpyrrolidine fumarate salt

品牌
Sigma-Aldrich
CAS
14976-57-9
货号
SML0445
包装型号
规格纯度
≥98% (HPLC)
参考价格
1193.78 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Clemastine fumarate is used to treat multiple sclerosis, sneezing and rhinorrhea linked to common cold. It stimulates oligodendrocyte progenitor cell (OPC) differentiation and myelination.

应用

Clemastine fumarate salt has been used as a stimulator of rodent oligodendrocyte generation and myelination in vitro and in vivo.

包装

100 mg in glass bottle

生化/生理作用

Clemastine fumarate is an antihistamine H1-antagonist and anticholinergic that also has antipruritic activity.

特点和优势

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式C21H26ClNO · C4H4O4
分子量459.96
EC 号239-055-2
MDL编号MFCD00137486
PubChem化学物质编号329824727
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
旋光性[α]/D +15 to +25°, c = 1 in methanol
储存条件desiccated
颜色 white to beige
溶解性DMSO: 5 mg/mL (clear solution; warmed)
储存温度room temp
SMILES stringOC(=O)\C=C\C(O)=O.CN1CCC[C@@H]1CCO[C@](C)(c2ccccc2)c3ccc(Cl)cc3
InChI1S/C21H26ClNO.C4H4O4/c1-21(17-7-4-3-5-8-17,18-10-12-19(22)13-11-18)24-16-14-20-9-6-15-23(20)2;5-3(6)1-2-4(7)8/h3-5,7-8,10-13,20H,6,9,14-16H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1+/t20-,21-;/m1./s1
InChI keyPMGQWSIVQFOFOQ-YKVZVUFRSA-N
Gene Informationhuman ... HRH1(3269)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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