Anti-Myosin X Antibody

产品说明

一般描述

Myosins are a superfamily of molecular motor proteins found in eukaryotic cells. Motor proteins are involved in muscular contraction, cytokinesis, short-range membrane/vesicle transport and a host of other cellular processes. The myosins are responsible for actin-based motility by using the energy of ATP hydrolysis to generate force and movement along actin filaments. There are many isoforms of myosin of which some have specialized functions in certain cell types (such as muscle), while other isoforms are ubiquitous. Myosin X belongs to a group of myosin isoforms known as unconventional myosins that participate in cellular processes ranging from membrane trafficking to signaling and cell motility. Myosin X is concentrated at the tips of filopodia and Myosin X rich regions travel forward and backward along filopods, (Berg, 2002). It also appears that Myosin X functions in actual filopodia formation, (Bohil, 2006).

特异性

Cat. No. AB1094 recognizes human Myosin X.
Predicted to cross react with mouse and rat based on 100% sequence homology. Reactivity with other species has not been tested.

免疫原

Epitope: a.a. 936-953
KLH-conjugated synthetic peptide to amino acids 936-953 of human Myosin X.

应用

Detect Myosin X using this Anti-Myosin X Antibody validated for use in WB.

质量

Evaluated on a representative lot by Western blot on human head/neck lysate using Anti-Myosin X.

目标描述

~ 108 kDa

储存及稳定性

Maintain at -20°C for up to 1 year from date of receipt.
Upon arrival, aliquot into usable quantities to avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

分析说明

Control
Human head/neck lysate.

法律信息

GenBank is a registered trademark of United States Department of Health and Human Services

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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