Anti-JARID1D Antibody

产品说明

一般描述

Also known as Lysine-specific demethylase 5D, this histone demethylase is specific for ′Lys-4′ of histone H3 and is known to play a central role in histone function and spermatogenesis. It demethylates trimethylated and dimethylated, but not monomethylated H3 ′Lys-4′. Uniprot.org states two different isoforms of this enzyme.

免疫原

KLH-conjugated linear peptide corresponding to human JARID1D.

应用

Use Anti-JARID1D Antibody (rabbit polyclonal antibody) validated in WB, ICC, IP to detect JARID1D also known as Lysine-specific demethylase 5D, Histocompatibility Y antigen, H-Y, Histone demethylase JARID1D.
Research Category
Epigenetics & Nuclear Function
Immunocytochemistry Analysis: 2 µg/mL from a representative lot detected JARID1D in mESCs.

Immunoprecipitation Analysis: A representative lot immunoprecipitated JARID1D in human testis tissue lysate.
Research Sub Category
Histone Modifying Proteins

质量

Evaluated by Western Blot in human testis tissue lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected JARID1D in 10 µg of human testis tissue lysate.

目标描述

~174 kDa observed. Two isoforms may be observed due to alternative splicing at a molecular weight of ~167 kDa and ~174 kDa in some cell lysates. An uncharacterized band at a molecular weight of ~255 kDa may be observed in some cell lysates.

外形

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
Human testis tissue lysate.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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